Sunday, December 31, 2017

What Are Epigenetics And Some Examples

By Jason Wagner


They can turn some genes off or on at some point. It is an external modification of DNA. Epigenetics, are traits that are above all the genes. It does not affect the sequence of the DNA, but it does how the DNA reads. It may live in the body of a person for as long as some cells are still alive. In others, it lasts in their life time from childhood to adulthood. It may also be passed over generations.

When DNA methylation is added to a methyl group or a chemical cap, it may cause some alteration to the genetic material. It alters the physical structure of the DNA but never the sequence. This can actually lead to the suppression of some genes. This means that those genes will not have the chance to be expressed. The structure will be the same, but the physical appearance will be different.

DNA wraps itself around a protein known as histone. This protein is what enables the comfortable accommodation of DNA inside a cell. Otherwise, the DNA will be too long to fit into one cell. If the histone is too tight on the DNA, the cell cannot recognize it. There are however modifications that relax histones so that the genetic material can be readable in cells.

Various genes express themselves differently depending on how strong and their functionality at different intervals. This is why the skin cell, brain cells, and muscle cells appear to be very different yet they have the same genetic composition. The fact that these cells are different is the reason why our body parts are also different. They, however, work together in order to conduct bodily functions and to the purpose they are intended to undertake on that instant.

As earlier mentioned, epigenetics can be passed from one generation to the next for a long time. This is likely to happen when they are present in the sperm cell, the egg cell or in both. However, it may not happen because of the reprogramming process. This occurs when the sperm and the egg cell combine to form a whole new cell. All the epigenetics may be erased. The fetus can start afresh.

This is however not always the case. Some of this genetics are resistant to the reprogramming process. This means that that genetics is going to be passed on to the child once the egg is fertilized. This means like factors such as food ingested before the conception of the child, may actually affect the future of the child. It is however yet to be proven in human beings.

Scientists seem to have the idea that some epigenetics have the ability to control cancer. Some epigenetics may suppress the ability of a cell to control its growth. The cell overgrows and begins to hinder the normal functioning of the body and the others surrounding it. This is what comes to be a tumor.

There are cells whose job is to reconstruct damaged DNA. Some epigenetics may cause this to be impossible. This means that DNA will be damaged continually with no way of getting repaired. This is one of the ways of letting cancer out.




About the Author:



No comments:

Post a Comment